4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
Product Name |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
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Product Code |
A00006897
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Chemical name |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one
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Synonyms |
α-Decitabine-3’,5’-bis(4-chlorobenzoate); Decitabine USP Related Compound C
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Impurity |
Decitabine USP Related Compound C
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CAS Number |
1140891-02-6
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Alternate CAS # |
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Molecular form |
C₂₂H₁₈Cl₂N₄O₆
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Appearance |
White to Off-White Solid
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Melting Point |
>200°C (dec.)
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Mol. Weight |
505.31
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Storage |
Hygroscopic, -20°C Freezer, Under Inert Atmosphere
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Solubility |
DMSO (Slightly), Methanol (Slightly, Heated)
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Stability |
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Category |
Amines, Aromatics, Heterocycles, Pharmaceuticals, Intermediates & Fine Chemicals
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Boiling Point |
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Applications |
4-Amino-1-[3,5-bis-O-(4-chlorobenzoyl)-2-deoxy-α-D-erythro-pentofuranosyl]-1,3,5-triazin-2(1H)-one (Decitabine USP Related Compound C) is a derivative of α-Decitabine (D226730) which is shown to inhibit DNA methylation resulting in an effective anticancer agent.
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Dangerous Goods Info |
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References |
Hajek, M. et al.: Biochem. Pharm., 75, 965 (2008); Rogstad, D. et al.: Chem. Res. Toxicol., 22, 1194 (2009);
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Extra Notes |
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Documents (MSDS) |
Download Document
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Keywords |
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